The Rise Fund Leads $5M Series A Investment in SystemOne, the Digital Backbone for Infectious Disease Diagnostics

Investment to Accelerate
linking every Diagnosis to Treatment starting with TB and HIV

Springfield, MA; Oct 2, 2018 -- SystemOne, the leader in global disease intelligence for rapid detection and response to infectious diseases and response, today announced a $5 million Series A investment led by The Rise Fund, a global impact investment fund managed by TPG Growth. Also participating in the round was EchoVC, B&Y Venture Capital Partners and strategic angel investors. EchoVC’s Eghosa Omoigui has joined SystemOne’s board of directors.

SystemOne’s platforms, GxAlert® and Aspect®, connect over 2000 diagnostic devices in 40+ countries, including Nigeria, Kenya, Pakistan, and Myanmar. Since its inception, SystemOne’s Aspect®  and GxAlert® platforms have automatically transmitted over 5 million diagnostic results, device performance data, and aggregate disease information to clinicians, healthcare ministries, and patients around the world.  Instant notifications and up-to-date dashboards provide over 50,000 alerts/month about test results, disease trends, device functionality, error rates and more.

“Information technology will fuel the next leap forward in stopping the most entrenched and crippling infectious diseases across the globe,” said Chris Macek, CEO of SystemOne. “Rapid and accurate movement of data will make global investments more effective, ensuring that health providers know where and when infectious diseases are happening, can get patients onto treatment and monitor outcomes.”

Before SystemOne, diagnostic results could take up to several months to reach health officials and patients. SystemOne’s technology connects any diagnostic device for any disease, moving results in real-time and providing health officials a single line of sight into the disease burden in their geographies. In diseases such as HIV and TB, where global funders spend $26 billion annually, such line of sight plays a critical role in optimizing investments and efforts for maximum benefit.

“We’re very excited to partner with SystemOne, to help advance innovative solutions that can bring us towards the global goal of ending tuberculosis and HIV,” said said Yemi Lalude, Partner at TPG Growth. “The company’s focus on reducing time to treatment and closing the  gaps between diagnosis and treatment – and treatment adherence – can help create significant social impact and drive economic progress in countries where HIV and TB are prevalent.”

The investment was sourced through TPG Growth’s strategic relationship with EchoVC Partners, the leading Africa-focused seed and early-stage venture capital fund that targets early to growth-stage deals in the technology sector. This follows earlier investments in companies such as Frontier Car Group and Gro Intelligence.

The investment in SystemOne will help the company accelerate linking positive diagnoses to treatment and eventually to outcome, playing a critical role in meeting and measuring international targets for TB and HIV.

About SystemOne
Founded in Massachusetts in 2012, SystemOne focuses on producing solutions for disease surveillance and response. SystemOne has offices in Springfield, MA and Johannesburg, South Africa. The company’s new disease intelligence software, Aspect®, addresses numerous infectious diseases including Zika, Ebola, HIV, Malaria, Hepatitis C and more on a host of diagnostic devices. To contact SystemOne, email: info@systemone.id

About The Rise Fund 
The Rise Fund is the world's largest global fund committed to achieving measurable, positive social and environmental outcomes alongside competitive financial returns —what we call "complete returns." The Rise Fund is managed by TPG Growth, the global growth equity and middle market buyout platform of alternative asset firm TPG. The Rise Fund is led by a group of influential thought leaders with a deep personal and professional commitment to driving social and environmental progress. The board includes: Bill McGlashan, TPG Growth Founder and Managing partner; Bono, Jeff Skoll, Mo Ibrahim, Laurene Powell Jobs, Anand Mahindra and Pierre Omidyar. The Rise Fund's objectives align with the U.N.'s Sustainable Development Goals. The Rise Fund invests in education, energy, food and agriculture, financial services, growth infrastructure, healthcare, and technology, media, and telecommunications companies that deliver complete returns. For more information, visit therisefund.com.

 About TPG Growth 
TPG Growth is the middle market and growth equity investment platform of TPG, the global private investment firm. With more than $13 billion of assets under management, TPG Growth targets investments in a broad range of industries and geographies. TPG Growth has the deep sector knowledge, operational resources, and global experience to drive value creation, and help companies reach their full potential. The firm is backed by the resources of TPG, which has more than $73 billion of assets under management. For more information, visit www.tpg.com.

Media Contacts
SystemOne
Nicolas Boillot
888.845.2610 x4
nboillot@systemone.id

The Rise Fund/TPG
Frank Thomas
212 601 4711
media@tpg.com

EchoVC Partners
press@echovc.com

SystemOne Launches RDT Digital Integration for Aspect Platform

First Commercial, Scalable Solution Works With Any RDT

Springfield, MA and Johannesburg, South Africa – August 14, 2018 - SystemOne, the leader in global disease intelligence for rapid detection and response, has announced the integration of off-the-shelf rapid diagnostic tests (RDTs) into the Aspect® platform. Although millions of RDTs are used worldwide for the detection of HIV, Malaria, and Influenza, there are few tools available to collect, aggregate, and validate RDT results in the field.

Because of recent pressure to move RDTs into self-testing by people at home, the global health community has sought a way to collect data, both to connect individual patients for follow-up testing and counseling, and to aggregate the data to study patterns of disease. Although academic groups have experimented with methods for reading RDT results and collecting patient data, none have found widespread use.

Working with the HSTAR Programme at University of the Witwatersrand Reproductive Health and HIV Institute (Wits RHI) and supported by funding from the Bill & Melinda Gates Foundation (BMGF), SystemOne developed its approach to be flexible, scalable, and sustainable.

By integrating RDT data into the Aspect platform, the data can be accessed within minutes by the ministry of health, research team, and healthcare providers anywhere in the world. Because Aspect already integrates HIV viral load data, the solution now makes it possible to link screening tests to confirmatory tests and follow-up testing during treatment.

For the first roll-out of the functionality, SystemOne created a mobile-phone application that collects demographic data about the patient, offers guidance for performing a self-test using standard RDT, and allows the patient to take a picture of the completed test result.

  A healthcare worker observing a patient performing HIV self-testing

A healthcare worker observing a patient performing HIV self-testing

  A patient using the mobile app to guide her through HIV self-testing instructions

A patient using the mobile app to guide her through HIV self-testing instructions

The app asks for the patient’s interpretation of the test result. All of the data, including the picture, are uploaded to Aspect for review by healthcare workers.

Because Aspect is flexible enough to accept diagnostic data from any device, other app providers can produce their own apps to guide patients, collect data, and even automatically interpret results. For developers, integration with Aspect is as simple as making a single call to Aspect, securely delivering clinical and demographic data.

  Sample Dashboard Combining HIV Self-testing and TB Reporting

Sample Dashboard Combining HIV Self-testing and TB Reporting

SystemOne products are used to collect, analyze, and deliver diagnostic data from any diagnostic device for diseases such as TB, HIV, Hepatitis, Ebola, and Zika. “We are especially excited to offer integration with RDTs,” says Aaron Oppenheimer, SystemOne VP of Product Design. “They are widespread and inexpensive, but the simplicity can come with a cost, since there has been no scalable way to gather the data. With this extension of the Aspect platform, healthcare programs can finally see what’s happening in the field, in real time.”

SystemOne Launches Action Dashboard for Laboratory and Treatment Management, Designed in Partnership with FIND

Provides Actionable Insights and Checklist-style Controls for Global Health Labs

Springfield, MA and Johannesburg, South Africa – July 30, 2018 - SystemOne, the leader in global disease intelligence for rapid detection and response, has launched a new approach for helping manage laboratories in global health settings. The “Action Dashboard” brings together a laboratory’s testing data and operational information in one place, giving laboratory managers at the local and regional levels unprecedented insights into laboratory operations, combined with user-friendly alerts about operational issues, such as devices in need of service, low stock levels, or communication issues.

Designed in partnership with the Foundation for Innovative New Diagnostics (FIND), the first Action Dashboard deployment is in Myanmar, which has been using GxAlert, SystemOne’s flagship platform for diagnostics connectivity, since 2014. The Action Dashboard represents a new level of features built on SystemOne’s next-generation platform, Aspect, with flexible, secure data management and advanced analyses in a simple, easy-to-read and easy-to-use form.

  Image: The TB dashboard keeps a program updated on testing statistics, progress against targets, and issues that need to be addressed in labs - all in real time.

Image: The TB dashboard keeps a program updated on testing statistics, progress against targets, and issues that need to be addressed in labs - all in real time.

“The Action Dashboard gives labs a straightforward list of issues and actions needed, from device maintenance to data collection, and lets regional officers see what’s happening in every laboratory. It supports configurable testing targets to allow a program to plan and track its coverage for different patient populations,” said Aaron Oppenheimer, VP of Product Design, SystemOne. “Working with FIND staff, and informed by members of the Clinton Health Access Initiative as well as the Myanmar National Tuberculosis Program helped us create the ideal tool for their environment.”

“FIND is committed to optimizing the use of diagnostic data to improve patient outcomes," said Catharina Boehme, CEO, FIND. "In Myanmar, we were able to combine the expertise of SystemOne with our knowledge of the issues faced by labs every day, to develop the Action Dashboard. The Action Dashboard improves decision making by providing both clinical and operational data to give a picture of how a disease management program is working, in real time.

SystemOne products are used to collect, analyze, and deliver diagnostic data from any diagnostic device for diseases such as tuberculosis, HIV, hepatitis, Ebola, and Zika. “Our focus is on flexibility,” said Oppenheimer. “There is no one-size-fits-all solution, so we have built our platform to be easily configurable to fit the needs of Ministries and implementing organizations working in any disease, in any country. We are already working to extend the Action Dashboard.”

First Tuberculosis-Focused Data Fellowship Program Helps TB Staff from Five Countries

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SystemOne, Management Sciences for Health and the Tableau Foundation Help Build Data Analytics Capacity in Tuberculosis Program Staff

July 25, 2018 – SystemOne LLC, (Springfield, MA), Management Sciences for Health (MSH) (Medford, MA) and the Tableau Foundation (Seattle, WA) recently concluded the first Data Fellowship Program for TB staff from the National TB programs and Ministries of Health. Eight participants from five participating countries attended the week-long training session in Johannesburg, using their own country’s GxAlert diagnostic data to uncover ways to improve healthcare delivery and patient impact.

“The TB Data Fellowship training is a breakthrough initiative to show the impact of data for developing effective and efficient control programs to end TB,” said Sarder Tanzir Hossain, Senior Technical Advisor, TB laboratories in Bangladesh.

“Tableau Desktop visualization has helped me to generate graphical presentations that have meaningful programmatic ‘stories’ to help drive and inform policy both at the program and ministry level,” said Lawrence Kachule, National GeneXpert Coordinator, NTP, MoH, Malawi.

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The Data Fellowship Program continues a year beyond this intensive first week, and will cover further training on how to analyze, visualize and understand data collected through GxAlert. The additional mentorship will be conducted remotely and will focus on continuing skills development and sharing of best practices.

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“Even though this was only the start of the program, by the end of the week, participants were able to begin exploring their own country data and developing visuals to improve the understanding and reporting for their TB program” said Natasha Gous, Medical Science Liaison and Facilitator of the TB Data Fellowship Program.

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DFatScreen.jpg
 The 2018 TB Data Fellows!

The 2018 TB Data Fellows!

About SystemOne
Founded in Massachusetts in 2012, SystemOne focuses on producing solutions for disease surveillance and response. SystemOne has offices in Springfield, MA and Johannesburg, South Africa. The company’s new disease intelligence software, Aspect®, addresses numerous infectious diseases including Zika, Ebola, HIV, Malaria, Hepatitis C and more on a host of diagnostic devices.

To contact SystemOne, email: info@systemone.id

SystemOne Launches Aspect Disease Intelligence Platform

Dramatic step forward in disease detection and response to link to treatment, curb outbreaks, and end epidemics

Springfield, MA and Johannesburg, South Africa – June 27, 2018 -  SystemOne today announced the launch of Aspect, a new disease intelligence platform based on the company’s work in over 40 countries. Aspect offers countries a proven means to understand disease burdens, accelerate response, and manage diagnostic equipment and supplies.  

Aspect is a completely new iteration of a product that began as GxAlert, the first platform to connect GeneXperts in 40+ countries, managing nearly 5 million TB, Ebola, and HIV diagnostic results. Aspect extends these capabilities to connect to any device and handle any diagnostic data in any country.

Aspect offers advanced features for clinical and operational control, and provides an extremely flexible platform, with easily customizable reports and SMS, email and dashboard communications. Some of Aspect’s features include:

  • Delivering diagnostic results to clinicians, supervisors, officials and even patients
  • Collecting and protecting patient data
  • Linking diagnosis to treatment
  • Stock-out prevention and supply management
  • Supply use-rate analysis and forecasting
  • Device utilization and maintenance analysis
  • Fully customizable communication and reporting features
  • Advanced user permissions to control data access
  • Easy integration with laboratory information systems or EMRs
  • World-class data protection and security
 Image: Aspect provides flexible operational and clinical dashboards, with data from lab devices, POC, and RDTs in one place to enable better, faster decisions.

Image: Aspect provides flexible operational and clinical dashboards, with data from lab devices, POC, and RDTs in one place to enable better, faster decisions.

“Medical diagnostics are the key to identifying and responding to disease as quickly as possible,” said Chris Macek, CEO of SystemOne. “Unfortunately, the power of diagnostics cannot be unlocked if data isn’t delivered and interpreted rapidly. If data can move faster than disease, humanity will win the fight against rapidly-spreading infectious diseases.”

“Today, around the world, our customers are deploying platforms ranging from electronic medical records (EMRs) to laboratory information systems,” said Aaron Oppenheimer, Product Manager for Aspect. “Our mission is to create the missing piece that ensures the rapid movement of actionable data through health systems, acting in concert with whatever other data systems a customer has. For regions or health systems that have no data infrastructure, Aspect can manage it all. Aspect ensures the right information gets to the right person at the right time in the cycle of care.”

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SystemOne, Management Sciences for Health and Tableau Foundation Join Forces to Improve use of TB Diagnostic Data

SystemOne, Management Sciences for Health and Tableau Foundation Join Forces to Improve use of TB Diagnostic Data

June 20, 2018 – SystemOne LLC, (Springfield, MA), Management for Health Sciences (MSH) (Medford, MA) and the Tableau Foundation (Seattle, WA) today announced a partnership designed to enable countries to better utilize and respond to the millions of infectious disease patient records being collected via SystemOne’s GxAlert and Aspect connected diagnostics platforms. This exciting new initiative, the TB Data Fellowship Program, will build the foundation for sustainable, in-country capacity to enhance the translation of diagnostic data into improved healthcare delivery and patient impact through the development of the next level of GxAlert user.

By using Tableau, the world’s leading visual analytics software, countries will learn how to explore, analyze, visualize and interpret their national TB program data.

Data fellows will develop the expertise and skills needed to identify program gaps and appropriate interventions in order to lower operating costs, improve the quality of the TB program, improve program management, reduce time to treatment and ultimately improve patient outcomes. 

SystemOne and TIMS Connect Diagnostics Across 8 Countries to Help Address TB in Mining Communities

May 30, 2018  – Springfield, MA, and Johannesburg, South Africa – SystemOne, a connected diagnostics company using data to drive healthcare impact and solutions, today announced its work with the program “TB in the Mining Sector in Southern Africa” (TIMS). Working together since early 2018, SystemOne and TIMS are connecting 11 diagnostic devices -- GeneXperts in this case -- in Occupational Health Service Centers across Botswana, Lesotho, Mozambique, Namibia, Swaziland, Tanzania, Zambia and Zimbabwe. These services include TB testing on the GeneXpert MTB/RIF assay.

These Occupational Health Service Centers face the challenge of monitoring TB testing and reporting for the program, ensuring instruments are working, and managing inventory for remote testing sites that are spread across 8 countries.

SystemOne is connecting all 11 instruments across the 8 countries to allow TIMS project coordinators located centrally in JHB, South Africa, to remotely monitor:

  • Number of tests being performed under the project

  • Instrument status (error rates, utilization rates, downtime)

  • Stock levels to ensure proper inventory management

Twilio Case Study

Twilio Case Study

Customer Stories: A SystemOne Case Study by Twilio

Working across 40 countries in the developing world, SystemOne collects data from diagnostic instruments and moves it, transparently, from the lab to clinics, ministries, and patients. They have also built intelligence into their system; in addition to moving test results, SystemOne provides a critical view into supply chain and device maintenance.